Exciting advancements have been made in gene, cell, and tissue engineering beyond the DNA level, bringing cutting-edge therapeutics to tackle a wide range of medical conditions. This session will delve into genome regulation, 'genetic tuning,' and bioprinted tissue therapeutics, exploring how these breakthroughs can be translated into personalized and effective treatments. Furthermore, we will also discuss the important ethical considerations while we are marking a significant leap forward in our fight against both common and complex diseases.